陳春霞
福建省三明真菌研究所!三明365000
【中文摘要】 羧甲基茯苓多糖(Carboxymethylpachymaran,CMP)12.5~100μg/ml對Nama-lwa類淋巴細(xì)胞、S801和S7811白血病細(xì)胞促誘生干擾素-α(IFN-α)效價(jià)比常規(guī)誘生高10~20倍;10μg/ml對人血淋巴細(xì)胞促誘生干擾素-γ(IFN-γ)效價(jià)比常規(guī)添生高8倍;100μg/ml對人血淋巴細(xì)胞促誘生白細(xì)胞介素-2(IL-2)效價(jià)可以達(dá)到2500IU/ml;20~100μg/ml可以刺激人外傷脾細(xì)胞產(chǎn)生淋巴毒素(Lymphotoxin,LT)及新抗癌淋巴因子—一白細(xì)胞調(diào)節(jié)素(Leukoregulin,LR)。
【英文摘要】 The valence of the stimulation effect of 12.5-100μg/ml CMP on interferon-(IFN-α) produced by Namalwa lymphoid cell, S801 and S7811 leukemia cells was 10-20 times greater than that produced by conventional agent. The valence of the stimulation effect of 100μg/ml CMP on interferon-γ (IFN-γ) produced by human blood lymphocyte was 8 times higher than that produced by conventional agent. The valence of the stimulation effect of 100μg/ml CMP on interleukin-2 (IL-2) produced by human blood lymphocyte could be as high as 2500IU/ml. The 20-100μg/ml CMP could stimulate human spleen cells to produce Lymphotoxin (LT) and a novel anticancer lymphokine--Leukoregulin (LR).
【中文關(guān)鍵詞】 羧甲基茯苓多糖; 促誘生; 干擾素; 白細(xì)胞介素; 淋巴毒素; 白細(xì)胞調(diào)節(jié)素
【英文關(guān)鍵詞】 Carboxymethylpachymaran; Stimulation effect; Interferon; Interleukin; Lymphoto- xin; Leukoregulin
【文獻(xiàn)出處】 食用菌學(xué)報(bào),Acta Edulis Fungi,編輯部郵箱,1996年01期 【DOI】CNKI:SUN:SYJB.0.1996-01-004